1.    Lin CH, Shyu CL, Wu ZY, Wang CM, Chiou SH*, Chen JY, Tseng SY, Lin TE, Yuan YP, Ho SP, Tung KC, Mao FC, Lee HJ, Tu WC*. 2023. Antimicrobial peptide mastoparan-AF kills multi-antibiotic resistant Escherichia coli O157:H7 via multiple membrane disruption patterns and likely by adopting 3-11 amphipathic helices to favor membrane interaction. Membranes 13: 251. (19 pages) (Impact factor 4.562, Ranking in Polymer Science 21/91 = 23%, SCI)

2.   Liu BR, Chiou SH, Huang YW, Lee HJ. 2022. Bio-membrane internalization mechanisms of arginine-rich cell-penetrating peptides in various species. Membranes 12:88. (9 pages) (Impact factor 4.562, Ranking in Polymer Science 21/91 = 23%, SCI)

3.   Holl NJ, Dey M, Huang YW, Chiou SH, Lee HJ. 2021. Lactoferricin-Derived L5a Cell-Penetrating Peptide for Delivery of DNA into Cells. Methods in Molecular Biology 2211: 113-122

4.     Lee HJ, Huang YW, Chiou SH, Aronstam RS. 2019. Polyhistidine facilitates direct membrane translocation of cell-penetrating peptides into cells. Scientific Reports 9: 9398. (Impact factor 4.38, Ranking in Multidisciplinary Sciences 17/73 =23.28%, SCI)

5.    Joseph NA, Chiou SH*, Lung Z, Yang CL, Lin TY, Chang HW, Sun SH*, Gupta SK, Yen L, Wang SD, Chow KC*. 2018. The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells. Journal of Hematology & Oncology 11: 74. (Impact factor 23.168, Ranking in Hematology 4/79 =5.0%, SCI, cited 60 times)

6.   Hung YC, Chen TC, Chiou SH*, Chow KC*, Lin TY, Chuang CS, Lin SH, Wu KH, Wang SD. 2018. Prenatal enterovirus 71 infection and its correlation with pediatric autistic patients – a possibility of non-genetic cause and the potential treatment target. Neuropsychiatry 8: 1940-1948

7.    Yang CL, Chiou SH*, Tai WC, Joseph NA, Chow KC*. 2017. Trivalent chromium induces autophagy by activating sphingomyelin phosphodiesterase 2 and increasing cellular ceramide levels in renal HK2 cells. Molecular Carcinogenesis 56: 2424-2433. (Impact factor 3.411, Ranking in Biochemistry & Molecular Biology 143/370=38.65%, SCI)

8.    Chen CC, Chiou SH, Yang CL, Chow KC, Lin TY, Chang HW, You WC, Huang HW, Chen CM, Chen NC, Chou FP, Chou MC. 2017. Secreted gelsolin desensitizes and induces apoptosis of infiltrated lymphocytes in the prostate cancer. Oncotarget 8: 77152-77167

9.   Yang PC, Chiou SH, Huang CW, Lee YJ. 2017. Systemic lupus erythematosus and Sjögren-like syndrome in a poodle. Taiwan Veterinary Journal 43: 17-21

10. Fan YH, Lin YL, Hwang YC, Yang HC, Chiu HC, Chiou SH*, Jong MH, Chow KC, Lin CC. 2016. T-cell factor-4 and MHC upregulation in pigs receiving a live attenuated classical swine fever virus (CSFV) vaccine strain with interferon-gamma adjuvant. Veterinary Journal 216: 148-156. (Ranking in Veterinary Sciences 25%, SCI)

11. Chen YC, Chi LM, Chow KC, Chiou SH*, Fan YH, Ho SP, Hsu YC, Hwang YC, Wu MX, Lee WM, Lin SL, Tsang CL, Mao FC. 2016. Association of anticardiolipin, antiphosphatidylserine, anti-β2 glycoprotein I, and antiphosphatidylcholine autoantibodies with canine immune thrombocytopenia. BMC Veterinary Research 12: 106. (Ranking in Veterinary Sciences 26/170=15.29%, SCI)

12. Chao YH, Wu KH, Chiou SH, Chiang SF, Huang CY, Yang HC, Chan CK, Peng CT, Wu HP, Chow KC, Lee MS. 2015. Downregulated CXCL12 expression in mesenchymal stem cells associated with severe aplastic anemia in children. Annals of Hematology 94: 13-22. (SCI)

13. Fang HY, Lin TY, Chiou SH, Wang LS, Chow KC. 2015. MicroRNA-22E Inhibits HER-3 Protein Expression to Facilitate Metastasis of Lung Adenocarcinoma. Journal of Cancer Therapy 6: 362-374

14. Chiu HC, Chow KC, Fan YH, Chang SC, Chiou SH*, Chiang SF, Chiou CH, Wu GH, Yang HC, Ho SP, Chen YK, Lee WC, Sun HS. 2013. Expression of EBV-encoded oncogenes and EBV-like virions in multiple canine tumors. Veterinary Microbiology 163: 79-89. (Impact factor 3.3, Ranking in Veterinary Sciences 12/170=7.05%, SCI)

15. You WC, Chiou SH, Huang CY, Chiang SF, Yang CL, Sudhakar JN, Lin TY, Chiang IP, Shen CC, Cheng WY, Lin JC, Shieh SH, and Chow KC*. 2013. Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma. Neuro-Oncology 15:1342-1352. (Impact factor 7.786, Ranking in Clinical Neurology 9/192=4.6%, SCI)

16. Chiang YY, Wang SL, Yang CL, Yang HY, Yang HC, Sudhakar JN, Lee CK, Huang HW, Chen CM, Chiou SH, Chiang SF, Fang HY, Chen CY, Shieh SH, Chow KC*. 2013. Extracts of Koelreuteria henryi Dummer induce apoptosis and autophagy by inhibiting dihydrodiol dehydrogenase to enhance anticancer effects. International Journal of Molecular Medicine 32: 577-584. (SCI)

17. Huang CY, Chiang SF, Lin TY, Chiou SH*, Chow KC*. 2012. HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction. PLoS ONE 7:e33657. (SCI, cited 88 times)

18. Chiang SF, Huang CY, Lin TY, Chiou SH*, Chow KC*. 2012. An alternative import pathway of AIF to the mitochondria. International Journal of Molecular Medicine 29:365-372. (SCI, cited 43 time)

19. Fang HY, Chen CY, Chiou SH, Wang YT, Lin TY, Chang HW, Chiang IP, Lan KJ, Chow KC. 2012. Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells. Human Pathology 43: 105-114 (Impact factor 3.3, Ranking in Pathology 18/79=22.78%, SCI)

20. Chen CY, Fang HY, Chiou SH, Yi SE, Huang CY, Chiang SF, Chang HW, Lin TY, Chiang IP, Chow KC. 2011. Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti-apoptotic activity in lung adenocarcinoma cells. Cancer Science 102:1582-1589. (Impact factor 6.518, SCI)

21. Cheng CF, Hung SW, Lin YH, Liu PC, Chen MH, Tu CY, Chang CH, Chiou SH, Wang WS. 2011. The effects of nitric oxide donors, cytokines, and lipopolysaccharide on apoptosis of the Tilapia head kidney-derived macrophages. Taiwan Veterinary Journal 37: 169-179

22. Chiang SF, Lin TY, Chow KC*, Chiou SH*. 2010. SARS spike protein induces phenotypic conversion of human B cells to macrophage-like cells. Molecular Immunology 47: 2575-2586. (Impact factor 4.174, SCI)

23. Huang KH, Chiou SH, Chow KC, Lin TY, Chang HW, Chiang IP, Lee MC. 2010. Overexpression of aldo-keto reductase 1C2 is associated with disease progression in patients with prostatic cancer. Histopathology 57: 384-394. (Impact factor 7.778, SCI)

24. Fang HY, Chang CL, Hsu SH, Huang CY, Chiang SF, Chiou SH, Huang CH, Hsiao YT, Lin TY, Chiang IP, Hsu WH, Sugano S, Chen CY, Lin CY, Ko WJ, Chow KC. 2010. ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma. Journal of Cell Science 123: 1171-1180. (Impact factor 5.235, SCI)

25. Shyu CL, Lin CC, Hsuan SL, Chiou SH, Chan JPW. 2010. Suppurative meningitis in a 7-day-old Formosan sambar deer (Cervus unicolor swinhoei) caused by Escherichia coli. Canadian Veterinary Journal 51: 308-310. (SCI)

26. Lin SL, C.-H. Lin, L.-C. Chan, C.-H. Huang, K.-C. Chow, and S.-H. Chiou*. 2009. Case report: Canine systemic lupus erythematosus diagnosed by the usage of recombinant hnRNP Gi protein. Taiwan Veterinary Journal 35: 100-106

27. Shyu CL, Shia WY, Tung KC, Zhang ZJ, Lee CS, Chou CC, Chiou SH, Lee WM. 2009. Case report: isolation of Aeromonas hydrophila from a dog with esophageal foreign body obstruction. Taiwan Veterinary Journal 35: 248-252

28. Wang CM, Shyu CL, Ho SP, Chiou SH*. 2008. Characterization of a novel thermophilic, cellulose-degrading bacterium Paenibacillus sp. strain B39. Letters in Applied Microbiology 47: 46-53. (SCI, cited 135 times)

29. Wu YF, Shien JH, Yin HH, Chiou SH, Lee LH 2008. Structural and functional homology among chicken, duck, goose, turkey and pigeon interleukin-8 proteins. Veterinary Immunology and Immunopathology 125: 205-215. (SCI, Ranking in Veterinary Sciences 27/138=19.56%)

30. Wu YF, Liu HJ, Shien JH, Chiou SH, Lee LH. 2008. Characterization of interleukin-1 beta expression in chicken macrophages in response to avian reovirus. Journal of General Virology 89:1059-1068. (Impact factor 5.141, Ranking in Biotechnology & Applied Microbiology, SCI)

31.  Chuang ST, Yang CL, Fan YH, Chiou SH, Chan JPW. 2008. Determination of serum amyloid in cattle. Taiwan Veterinary Journal 34: 19-24.

32.  Chen JT, Huang CY, Chiang YY, Chen WH, Chiou SH, Chen CY, Chow KC. 2008. HGF increases cisplatin resistance via down-regulation of AIF in lung cancer cells. American Journal of Respiratory Cell and Molecular Biology 38: 559-565. (Impact factor 6.5, Ranking in Respiratory System 20%, SCI)

33.  Gau BH., Chu IM, Huang MC, Yang KT, Chiou SH, Fan YH, Chen MY, Lin JH, Chuang CK, Huang SY, Lee WC. 2008. Transcripts of enriched germ cells responding to heat shock as potential markers for porcine semen quality. Theriogenology 69: 758-766. (Ranking in Veterinary Sciences 12.35%, SCI)

34.  Kuo S J, Wang HC, Chow KC, Chiou SH, Chiang SF, Lin TY, Chiang IP, Chen DR. 2008. Expression of rTSs as a 5-fluorouracil resistance marker in patients with primary breast cancer. Oncology Report 19: 881-888. (Impact factor 4.136, SCI)

35.  Hsu NY, Chen CY, Hsu CP, Lin TY, Chou MC, Chiou SH, Chow KC. 2007. Prognostic significance of expression of nm23-H1 and focal adhesion kinase in non-small cell lung cancer. Oncology Report 18: 81-85. (Impact factor 4.136, SCI)

36.  Wang CM, Shyu CL, Ho SP, Chiou SH*. 2007. Species diversity and substrate utilization patterns of thermophilic bacterial communities in hot aerobic poultry and cattle manure composts. Microbial Ecology 54: 1-9. (Impact factor 4.192, Ranking in Marine & Freshwater Biology 4/104=3.84%, SCI) cite 49 times

37.  Wang WS, Hung SW, Lin YH, Tu CY, Wong ML, Chiou SH, Shieh MT. 2007. The effects of five different glycans on innate immune responses by phagocytes of hybrid tilapia and Japanese eels Anguilla japonica. Journal of Aquatic Animal Health 19: 49-59.

38.  Yang KT, Lin CY, Liou JS, Fan YH, Chiou SH, Huang CW, Wu CP, Lin EC, Chen CF, Lee YP, Lee WC, Ding ST, Cheng WT, Huang MC. 2007. Differentially expressed transcripts in shell glands from low and high egg production strains of chickens using cDNA microarrays. Animal Reproduction Science 101: 113–124. (Ranking in Agriculture, Dairy & Animal Science 6/54=11.1%, SCI)

39.  Fan YH, Chow KC, Huang SY, Chi LM, Huang C, Chiou SH*. 2007. A missense polymorphism in porcine interferon-γ cDNA affects antiviral activity of the protein variant. Molecular Immunology 44: 3297-3304. (Impact factor 4.174, Ranking in Biochemistry & Molecular Biology, SCI)

40.   Wu YF, Liu HJ, Chiou SH, Lee LH. 2007. Sequence and phylogenetic analysis of interleukin (IL)-1b-encoding genes of five avian species and structural and functional homology among these IL-1b proteins. Veterinary Immunology and Immunopathology 116: 37-46. (SCI, Ranking in Veterinary Sciences 27/138=19.56%)

41.  Lin TS, Huang HH, Fan YH, Chiou SH*, Chow KC*. 2007. Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer. Oncology Report 17: 565-572. (Impact factor 4.136, SCI) cite 16 times

42.  Hung SW, Lin YH, Tu CY, Wong ML, Chiou SH, and Wang WS. 2007. Effects of cytokines and lipopolysaccharide on the functions of tilapia head kidney-derived macrophages. Taiwan Veterinary Journal 33: 96-103.

43.  Tai HL, Lin TS, Huang HH, TLin TY, Chou MC, Chiou SH*, Chow KC*. 2007. Overexpression of aldo-keto reductase 1C2 as a high-risk factor in bladder cancer. Oncology Report 17: 305-311. (Impact factor 4.136, SCI) cite 18 times

44.   Fan YH, Lin CD, Chiou SH*, Chow KC, Chi YS, Lee LH, Shien JH, Shieh HK. 2006. Differential expression of U2AF³⁵ in the arthritic joint of avian reovirus-infected chicks. Veterinary Immunology and Immunopathology 114: 49-60. (Ranking in Veterinary Sciences, SCI)

45.  Liu YL, Fan YH, Chow KC, Chi LM, Tung KC, Chiou SH*. 2006. Expression of a bioactive murine interleukin-18 protein. Taiwan Veterinary Journal 32: 93-100.

46.  Lin TY, Chan LC, Fan YH, Lin CH, Chow KC, Lin SL, Lan JL, Lin FJ, Chiou SH*. 2006. Use of a recombinant protein containing major epitopes of hnRNP G to detect anti-hnRNP G antibodies in dogs with systemic lupus erythematosus. Research in Veterinary Science 81: 335-339. (SCI, Ranking in Veterinary Sciences)

47.  Ueda M, Hung YC, Chen JT, Chiou SH, Huang HH, Lin TY, Terai Y, Chow KC. 2006. Infection of human papillomavirus and overexpression of dihydrodiol dehydrogenase in uterine cervical cancer. Gynecologic Oncology 102: 173-181. (Impact factor 4.7, Ranking in Obstetrics & Gynecology, 14/86=16.28%, SCI) cite 23 times

48.  Yen SK, Chiou SH, Wu SJ, Chang CC, Lin SP, Lin CM. 2006. Characterization of electrolytic HA/ZrO₂ double layers coatings on Ti—6Al—4V implant alloy. Materials Science Engineering: C 26: 65-77. (SCI)

49. Chen JT, Lin TS, Chow KC, Huang HH, Chiou SH, Chiang SF, Chen HC, Chuang TL, Lin TY, Chen CY. 2006. Cigarette smoking induces overexpression of HGF in type II pneumocytes and lung cancer cells. American Journal of Respiratory Cell and Molecular Biology 34: 264-273. (Impact factor 6.4, Ranking in Respiratory System 20%, SCI)

50. Cheng WC, Liau MC, Wu JT, Shyu CH, Cheng CH, Chiang KC, Chiou SH, Shien JH, Shyu CL, Cheng FP. 2005. Proliferation inhibition of DMGT and LM tk^- cell lines by application of CDA-II and high-doses vitamin C and vitamin K₃. Taiwan Veterinary Journal 31: 128-137

51. Chiou SH^*, Chow KC, Yang CH, Chiang SF, Lin CH. 2005. Discovery of Epstein-Barr virus (EBV)-encoded RNA signal and EBV nuclear antigen leader protein DNA sequence in pet dogs. Journal of General Virology 86: 899-905 (Impact factor 3.8, Ranking in Biotechnology & Applied Microbiology = 8.28%, SCI)

52. Tsai ST, Fan YH, Lee LH, Chiou CJ, Shieh HK, and Chiou SH^*. 2005. Recombinant protein expression and polyclonal antibody development of chicken interleukin-2. Taiwan Veterinary Journal 31: 256-263

53.  Lin TS, Chiou SH, Wang LS, Huang HH, Chiang SF, Shih AYH, Chen YL, Chen CY, Hsu CP, Hsu NY, Chou MC, Kuo SJ, Chow KC. 2004. Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer. Oncology Report 12: 717-723. (Impact factor 4.136, SCI) Cited 36 times

54.  Chiou SH, Lan JL, Lin SL, Chen DY, Tsai NY, Kuan CY, Lin TY, Lin FJ, Lee WM, Chang TJ. 2004. Pet dogs owned by lupus patients are at a higher risk of developing lupus. Lupus. 13: 442-449. (SCI)

55.  Chow KC, Hsiao CH, Lin TY, Chen CL. Chiou SH. 2004. SARS viral RNA. (letter) American Journal of Clinical Pathology 122: 474-475 (Impact factor 3.5, SCI)

56.  Chow KC, Hsiao CH, Lin TY, Chen CL. Chiou SH. 2004. Detection of severe acute respiratory syndrome-associated coronavirus in pneumocytes of the lung. American Journal of Clinical Pathology 121: 574-580. (Impact factor 3.5, SCI) Cited 31 times

57.  Chang YP, Chiou SH, Chang TC. Evaluation of the therapeutic effect of the Chinese herb Ixeris chinensis on Lupus-like NZB/NZW F1 mice. Taiwan Veterinary Journal 29: 386-392

58.  Chow KC, Chiou SH, Ho SP, Tsai MH, Chen CL, Wang LS, Chi KH. 2003. The elevated serum interleukin-6 correlates with the increased serum butyrate level in patients with nasopharyngeal carcinoma. Oncology report, 10:813-819. (Impact factor 4.136, SCI) Cited 30 times

59.  Yang MD, Wu CC, Chiou SH, Chiu CF, Lin TY, Chiang YP, Chow KC. 2003. Reduction of dihydrodiol dehydrogenase expression in the resected hepatocellular carcinoma. Oncology Report 10:271-276. (Impact factor 4.136, SCI) Cited 21 times

60.  Wang CM, Chiou SH, Ho SP, Ueng JS, Lin JA, and Shyu CL. 2002. Investigation of bacterial flora in aerobic composting. Journal of the Chinese Society of Veterinary Science 28:228-234

61.  Tsai MH, Chiou SH, Chow KC. 2001. Effect of platelet activating factor and butyrate on the expression of interleukin-2 receptor alpha in nasopharyngeal carcinoma cells. International Journal of Oncology, 19: 1049-1055.

62.  Lin SL, Chiou SH, Kuan CY, Wang LH, Ku CH, Lan JL. 2000. Canine lupus: the first case report in Taiwan. Journal of the Chinese Society of Veterinary Science 26: 309-316

63.  Wu HY, Chiou SH, Shien JH, Chang PC, Shieh HK. 1999. Detection of proteins and nucleic acids of Newcastle disease virus in Eimeria acervulina. Avian Pathology, 28: 441-445

64.  Chiou SH, Tsai NY, Mao FC, Ho SP. 1999. Expression of recombinant human interferon gamma in Escherichia coli. Taiwan Journal of Veterinary Medicine and Animal Husbandry, 69: 1-10

65.  Chiou SH, Freed EO, Panganiban AT, Kenealy WR. 1992. Studies on the role of the V3 loop in human immunodeficiency virus type 1 envelope glycoprotein function. AIDS Res. Human Retroviruses 8: 1611-1618. (SCI, Cited 24 times)

66.  Chiou SH, Hu MC, Chung BC. 1990. A missense mutation at Ile172 → Asn or Arg356 → Trp causes steroid 21-hydroxylase deficiency. Journal of Biological Chemistry 265: 3549-3552. (Impact factor 5.485, SCI, Cited 178 times)

1. Chiou SH, Chow KC, Shien JH, Fan YH, Lin PH, Wu PS. 2021年11月16日核發CA (Canada), 2893981. Date of patent: from Dec 5, 2012 to Dec 5, 2032.
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